Monosodium Phosphate Sodium Phosphate Monobasic Manufacturers NaH2PO4

Anmol Chemicals is the pioneer manufacturers of Sodium phosphate monobasic dibasic tribasic, Pharmaceutical Excipients Fragrance Food & Flavor chemicals in India. We offer Halal and Kosher Sodium phosphate monobasic dibasic tribasic made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Sodium phosphate monobasic dibasic tribasic is in these pages.

The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal

Monobasic sodium phosphate monobasic Monosodium Phosphate IP BP Ph EurUSP ACS Analytical Reagent FCC Food Grade Manufacturers

Monobasic Sodium Phosphate Monobasic

Mono Sodium Phosphate or Monosodium Phosphate (NaH2PO4, MSP), also known as anhydrous monobasic sodium phosphate or monosodium phosphate or sodium phosphate monobasic, is used as a laxative and, in combination with other sod. phos., as a pH buffer.

The pKa is 7.20. The sodium chloride equivalent value, or E-Value, is 0.49. It is soluble in 4.5 parts water. Monosodium phosphate is most commonly available as colorless crystals or a white powder. Sodium phosphate monobasic is insoluble in alcohol.

Specifications of Sodium Dihydrogen Phosphate Monohydrate BP Ph Eur
NaH2PO4-H2O, 138.0, CAS Number 10049-21-5
Action and use: Excipient.

DEFINITION
Sodium Dihydrogen Phosphate Monohydrate contains not less than 98.0% and not more than 100.5% of NaH2PO4, calculated with reference to the dried substance.

CHARACTERISTICS
Colourless crystals or a white powder.
Very soluble in water; very slightly soluble in ethanol (96%).
Dissolve 10.0 g in sufficient carbon dioxide-free water prepared from distilled water to produce 100 ml (solution S).

IDENTIFICATION
A. Solution S is faintly acid.
B. Solution S yields the reactions characteristic of phosphates.
C. Solution S neutralized with a 10% w/v solution of potassium hydroxide yields reaction A characteristic of sodium salts.
D. Complies with the test for Loss on drying.

TESTS
Acidity: pH of a mixture of 5 ml of solution S and 5 ml of carbon dioxide-free water , 4.2 to 4.5.
Clarity and colour of solution: Solution S is clear and colourless.
Arsenic: 0.5 g complies with the limit test for arsenic - 2 ppm.
Heavy metals: 12 ml of solution S complies with limit test A for heavy metals. Use lead standard solution (1 ppm Pb) to prepare the standard (10 ppm).
Iron: 10 ml of solution S complies with the limit test for - iron 10 ppm.
Chloride: Dilute 2.5 ml of solution S to 15 ml with water. The resulting solution complies with the limit test for chlorides - 200 ppm.
Sulphate: To 5 ml of solution S add 0.5 ml of hydrochloric acid and dilute to 15 ml with distilled water. The resulting solution complies with the limit test for sulphate - 300 ppm.
Reducing substances: To 5 ml of solution S add 0.25 ml of 0.02M potassium permanganate and 5 ml of 1M sulphuric acid and heat in a water bath for 5 minutes. The solution retains a slight red colour.
Loss on drying: When dried to constant weight at 130°, loses 11.5 to 14.5% of its weight. Use 0.5 g.

Specifications or Monobasic Sodium Phosphate USP NF
Monobasic Sodium Phosphate
NaH2PO4·xH2O
(anhydrous) 119.98
Phosphoric acid, monosodium salt, monohydrate.
Monosodium phosphate monohydrate 137.99 [CAS Number 10049-21-5]
Phosphoric acid, monosodium salt, dihydrate
Monosodium phosphate dihydrate 156.01 [CAS Number 13472-35-0]
Anhydrous [CAS Number 7558-80-7]

Monobasic Sodium Phosphate contains one or two molecules of water of hydration, or is anhydrous. It contains not less than 98.0 percent and not more than 103.0 percent of NaH2PO4, calculated on the anhydrous basis.

Identification: A solution (1 in 20) responds to the tests for Sodium 191 and for Phosphate.
pH: between 4.1 and 4.5, in a solution containing the equivalent of 1.0 g of NaH2PO4·H2O in 20 mL of water.
Water: less than 2.0% (anhydrous form); between 10.0% and 15.0% (monohydrate); between 18.0% and 26.5% (dihydrate).
Insoluble substances: Dissolve a portion equivalent to 10.0 g of NaH2PO4·H2O in 100 mL of hot water, filter through a tarred filtering crucible, wash the insoluble residue with hot water, and dry at 105 for 2 hours: the weight of the residue so obtained does not exceed 20 mg (0.2%).
Chloride: A portion equivalent to 1.0 g of NaH2PO4·H2O shows no more chloride than corresponds to 0.20 mL of 0.020 N hydrochloric acid (0.014%).
Sulfate: A portion equivalent to 0.20 g of NaH2PO4·H2O shows no more sulfate than corresponds to 0.30 mL of 0.020 N sulfuric acid (0.15%).
Aluminum, calcium, and related elements: A solution containing the equivalent of 1.0 g of NaH2PO4·H2O in 10 mL of water does not become turbid when rendered slightly alkaline to litmus paper with 6 N ammonium hydroxide.
Arsenic: the limit is 8 ppm.
Heavy metals: the limit is 0.002%.

Sodium Phosphate Monobasic FCC Food Grade Specifications
Monosodium Phosphate; Sodium Biphosphate;
Monosodium Dihydrogen Phosphate
NaH2PO4 Formula wt, anhydrous 119.98
NaH2PO4·H2O Formula wt, monohydrate 137.99
INS: 339(i) CAS: anhydrous [CAS Number 7558-80-7]
CAS: monohydrate [CAS Number 10049-21-5]

DESCRIPTION
Sodium Phosphate, Monobasic, is anhydrous or contains one or two molecules of water of hydration and is slightly hygroscopic. The anhydrous form occurs as a white, crystalline powder or granules. The hydrated forms occur as white or transparent crystals or granules. All forms are freely soluble in water, but are insoluble in alcohol. The pH of a 1:100 solution is between 4.1 and 4.7.
Function: Buffer; emulsifier; nutrient.

REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Phosphate and for Sodium.
Assay: Not less than 98.0% and not more than 103.0% of NaH2:PO4 after drying.
Arsenic: Not more than 3 mg/kg.
Fluoride: Not more than 0.005%.
Insoluble Substances: Not more than 0.2%.
Lead: Not more than 4 mg/kg.
Loss on Drying Anhydrous: Not more than 2.0%; Monohydrate: Between 10.0% and 15.0%; Dihydrate: Between 20.0% and 25.0%.

Sodium Phosphate, Monobasic, Monohydrate
Sodium Dihydrogen Phosphate Monohydrate
NaH2PO4-H2O
Formula Wt 137.99
CAS Number 10049-21-5

REQUIREMENTS
Assay: 98.0-102.0% NaH2PO4 - H2O
pH of a 5% solution: 4.1-4.5 at 25C

MAXIMUM ALLOWABLE
Insoluble matter: 0.01%
Chloride (Cl): 5 ppm
Nitrogen compounds (as N): 0.001%
Sulfate (SO4): 0.003%
Calcium (Ca): 0.005%
Potassium (K): 0.01%
Heavy metals (as Pb): 0.001%
Iron (Fe): 0.001%

Monobasic sodium phosphate monobasic Monosodium phosphate IP BP Ph Eur USP FCC ACS Manufacturers

Anmol Chemicals
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564 - FAX: 91-22-23728264

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Specification of Monosodium Phosphate Crystals Monobasic Sodium Phosphate Monobasic Crystals	Specification of Monosodium Phosphate Anhydrous Monobasic Sodium Phosphate Monobasic Anhydrous
P2O5 Content= 44% Assay= 98% Loss on Drying= Less than 24% pH of 2% Solution= 4.4-5 Insoluble= 0.025%	P2O5 Content= 59% Assay= 98% Loss on Drying= 1% pH of 2% Solution= 4.4-5 Insoluble= 0.5%